This guide was created to combat some of misinformation on the web about cold lasers and PhotoBioModulation (PBM). This is a no-nonsense guide to cold lasers and high dosage lasers ranging from low-cost home system to high-end systems for practitioners. You can use this guide in conjunction with our therapy laser comparison table to see most of the major players in the cold laser market and how they stack up based on specs and prices. There are over 4000 clinical studies and hundreds of books, video and other resources showing the effectiveness of laser therapy that you can search using the Laser-Therapy.US research tool. There are over 300,000 health care providers using cold lasers in their practice and over 750,000 laser users so laser therapy is not an "experimental" therapy as the insurance companies like to say when they deny a claim for a laser.

Even though, most tradition MDs stay away from laser therapy, they are widely used by chiropractors, acupuncturist, physical therapist, herbalist, function medicine specialist, vets, dentist, podiatrist and many other health care providers that focus on root health care corrections versus coping with the symptoms. Although lasers are not a cure all, there should be little doubt that cold lasers are effective in treating a wide variety of problems. The majority of therapeutic lasers are used to treat damaged tissue and structural (bone, joint and ligament) problems but the use of laser to treat trigger points, acupoints and lymph nodes is rapidly growing. Most therapeutic cold lasers have a treatment area between the size of a quarter to the size of a silver dollar, but systems created for trigger point and acupoint therapy focus the energy into a concentrated beam. Cold lasers are cleared for pain reduction, inflammation reduction and increasing blood flow.

The main 3 specs that people use to compare systems are:

  • 1. Power:
  • Power is measured in milliwatts [mW] for class 1 to 3b and watts [W] for class 4 systems.
  • 2. Wavelength
  • Wavelength is measured in nanometers [nm]. Each wavelength interacts with cells differently.
  • 3. Pulsing Options
  • Some systems are continuous wave [CW] only. Some are pulsing only. Some are both. Some problems are best solved with pulsing and some problems are best solved with CW.

These variables control the quality of light and how it travels though and reacts with tissue. Dosage is the measure of total light energy put into the tissue. It measured in Joules. Many people also care about the warranty, servic and training associated with the laser. Please call for specifics about each option.

In general, a laser's ability to successfully treat a wide variety of conditions is mostly based on output power at an appropriate wavelength with some contribution added from pulsing.

In general, the addition of pulsing to laser therapy reduces how quickly you build up the energy dosage but for a fixed treatment time, the addition of pulsing makes up for the lower dosage and then some. The best option is to set the laser on pulsing and increase the treatment time to achieve the same dosage. Most of the scientific research is focused on dosage (which is the total energy put into the treatment area). There is less emphasis in the research on using exotic wavelengths and pulsing frequencies but there is still some evidence that it is important too.

Based primarily on Dr. Hamblin's research and publications, we prefer 800nm to 860nm for nervous system and vascular issues. Followed by 600nm to 660nm. 980nm is the preferred option for pain control and 905nm is preferred for blood work and where safety is the highest priority. At this point, it appears that all the wavelengths are appropriate for treating structural or cellular damage.

Much of the misinformation about cold lasers is related to power levels and how they affect the safety and effectiveness of the product. Low power laser manufacturers have lots of ways to justify why their product is the best, but the overall market agrees that power is the single most important factor in determining the efficacy of cold lasers. With the exception of some class 4 lasers (which might have the capability to burn tissue if used incorrectly), more power is better because it allows practitioners to give patients higher dosage when it is appropriate. Many laser manufacturers have a doctor on staff who can write a recommendation letter to make sure that each buyer is getting supervision and training.


Lasers come in classes 1 through 4:

  • Class 1 & 2 lasers are can be purchased for use at home over-the-counter for use on humans and they have a maximum power of 5mW continuous per diode. Several manufacturers make higher power lasers that qualify as a class 1 or 2 by pulsing the laser. Without a recommendation for a health care provider like the ones listed above, a pulsing laser is the best option. Just don't waste your time buying anything that looks like a laser pointer.
  • Class 3 lasers are designed for practitioners but can be purchased for use on humans at home with the recommendation of a health care provider. They can be purchased without any restrictions for use on pets and horses. Class 3 lasers must be less than 500mW per laser diode continuous output. Several manufacturers have higher power units that use multiple diodes that have TOTAL power level in the class 4 range, but they are safe enough to qualify as a class 3b device because they have less chance of eye damage and no chance of tissue heating damage. Many laser manufacturers have a doctor on staff who can write a recommendation letter to meet the requirements, so we can sell you a laser.
  • In general, class 4 lasers are any laser that has one or more laser beams with an output of 500mW or more (Avant tested their system to prove that they can deliver class 3b safety out of 700mW diodes. Class 4 lasers between 0.5 watt and 60 watts can do damage to the eye or tissue if improperly used. This danger is easily eliminated with training. The FDA has softened the standards so that Class 4 lasers can be sold for home use. Some laser manufacturers have a doctor on staff who can train new owners on how to get the best results with their laser.



  • The next factor regarding cold laser effectiveness is the wavelength of the light. Because there is a therapeutic window where energy is best transferred into tissue, most laser operate in the 635nm (Red), the 810 nm (IR), and the 900 to 1080nm (IR) range. All 3 wavelengths have advantages and disadvantages.
  • 600nm to 660nm wavelength is best for shallower treatments, treating lymphatic issue, acupoint therapy, skin issues and for treating shallow areas. It is also commonly used for more complex problems because much of the energy is absorbed by the blood which flow throughout the body activates different problem areas. Because of the unique properties of this wavelength, it is commonly used in cosmetic lasers.
  • 800nm to 860nm is the sweet spot for combining maximum penetration depth and maximum photo-chemical reaction. Some laser gurus like Dr. Weber and Dr. Hamblin promote 810 nm as the optimum wavelength because it produces the maximum interaction with the mitochondria.
  • 900nm to 1080 nm is very popular with 910nm being the standard for all superpulsing lasers and 980nm being the standard for many class 4 systems. At 980nm, much of the energy is converted to heat and absorbed by the water in the tissue so it is less efficient than 810nm at creating photobiomodulation but many class 4 lasers just make up for the inefficiency with more power. These higher wavelenghts also provide great inflammation and pain control.

The best lasers offer multiple wavelengths. This gives you more flexibility in treating a wider range of problems.

Pulsing Versus Continuous

The next factor to consider is pulsing frequency and/or continuous wave operation. A laser can be turned on and off quickly to pulse the laser or it can sweep (operate at a constantly changing pulse frequency). Companies like Erchonia use extremely low power lasers (less than 20mW) and claim that all the" heavy lifting" is done with the pulsing and not the dosage. There is also a theory that the cells can become acclimated to any type of continuous input including continuous wave lasers and the pulsing helps keep the body from becoming desensitized to the laser therapy.

Continuous Wave (CW) light is best for getting higher dosages quickly so companies like Apollo make only CW laser. They say that no one knows what the best pulsing frequency is so why waste your time guessing and increasing the treatment times. More expensive lasers do both because sometimes you want the maximum dosage to give people an immediate improvement in their symptoms and sometimes you are OK with a lower dosage if you can get a stronger stimulation effect in the cells. Some conditions can take months of treatments, so some people might give up if they don't see an immediate improvement and stop the therapy. To prevent quitting, many practitioners start out the therapy routine with a higher dosage and then bring it down over time. Lasers with both continuous wave and pulsed wave allow practitioners and home users to optimize each treatment protocol based on the condition and the patient's expectations.

A recent summary study of laser therapy research by Huang et all came to the conclusion that pulsing is best for most applications except nervous system therapy.

There are a handful of other things to consider. This includes the quality of training (we offer the best in the industry), support literature and the depth of their protocol library. Practitioners often put a high value on flexibility and power while home owner want an easy to use product and safe. If you are looking at a system on sketchy webistes (that can cost less $2000), you might want to read our article about laser scams and questionable products.

In general, more powerful laser provide faster results and shorter treatment times so it can be good to buy as much power as you can afford.

Where to Start

Class 4: If you are a practitioner who is concerned about faster recoveries, shorter treatment times and you have a structured environment, start looking at the class-4 lasers like the ReGen Laser or EVOlaser. These elite lasers that offer the option for high dosages and/or quick treatment times. This system have mutli-step internal protocols so it is really easy to get amazing results you first day with the laser. If you are a practitioner who wants a simple, yet powerful laser, with no risk of tissue heating, look the Apollo desktop and portable. These systems can be overkill for laser acupuncture except the Apollo which offers an optional 500mW pinpoint probe and point finder.

If you are looking for a hands-free class-4 systems, the ReGen Laser and the EVOLaser offer hands-free options.

Class 3: The best overall value in class-3 lasers are the Avant LZ30p, LZ30x and LZ30z portables. They blow away the competition (like Erchonia™) based on the specs and the Avant systems do everything well. The Avant Lasers offer both RED and IR wavelengths, both pulsing and CW output, both broad and pinpoint treatments in one compact package. Another great handheld option is the PowerMedic Pro laser, their acupuncture probe is one of the best option because it is optimized for that application. For a desktop class 3 system, consider the Chattanooga Vectra Genisys (professionals only). Chattanooga is somewhat of a industry standard in PT and they make multi-modality systems. For unattended treatments, consider the Avant with a stand. We also sell the lengendary ML830™.

Class 1, 2 & 1m: If safety is a high priority, the TerraQuant/MR4 series laser are simply the best. There are probably more TerraQuant lasers in the world than all the other brands put together. Because they use super-pulsing technology, they have higher peak power level than you can normally get in a sub 3b class laser. Just stay away from anything that looks a laser pointer as these systems are legally limited to 5mW and deliver such a tiny dosage that most people would consider them worthless. Class 1m lasers are limited to 500mW (the same as a class 3b) but cannot cause eye damage unless the laser is focused through a lens. Therefore, a class 1m can be 100 times stronger than a class 2 or class 1.

View all the major brands on the market

We know it can be confusing. If you need help, please call us at 1-800-388-0850. We will be happy to answer any question about therapy lasers and we can make specific recommendations based on your needs.

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